Global Diabetic Neuropathy Treatment Market Size To Exceed USD 10.37 Billion by 2035 | CAGR of 7.61% : Forecast Analysis Report

RELEASE DATE: Aug 2025 Author: Spherical Insights
The Global Diabetic Neuropathy Treatment Market Size is Expected To Grow from USD 4.63 Billion in 2024 to USD 10.37 Billion by 2035, at a CAGR of 7.61% during the forecast period 2025-2035

Table of Contents

Global Diabetic Neuropathy Treatment Market Size, Share, and COVID-19 Impact Analysis, By Disorder Type (Peripheral Neuropathy, Autonomic Neuropathy, Proximal Neuropathy, and Focal Neuropathy), By Drug Class (NSAIDs, Capsaicin, Opioid, Antidepressants, and Others), and By Region (North America, Europe, Asia-Pacific, Latin America, Middle East, and Africa), Analysis and Forecast 2025 - 2035.


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  • As per Spherical Insights & Consulting, The Global Diabetic Neuropathy Treatment Market Size is Expected To Grow from USD 4.63 Billion in 2024 to USD 10.37 Billion by 2035, at a CAGR of 7.61% during the forecast period 2025-2035, owing to the launch of new therapies in the market and the rise in the number of cases.

 

  • The leading Diabetic Neuropathy Treatment Market Companies such as Pfizer Inc., Eli Lilly and Company, GlaxoSmithKline plc, Novartis AG, Teva Pharmaceutical Industries Ltd., Abbott Laboratories, Janssen Pharmaceuticals, NeuroMetrix Inc., Astellas Pharma Inc., Boehringer Ingelheim, Sanofi S.A., Daiichi Sankyo Company Ltd., UCB Pharma, Grunenthal GmbH, Vertex Pharmaceuticals, and Others.

 

 

Diabetic Neuropathy Treatment Market: Understanding and Treatment Algorithm:

Diabetic Neuropathy is a common complication of diabetes characterized by nerve damage caused by high blood sugar levels. It leads to symptoms like pain, tingling, numbness, and weakness, primarily in the hands and feet. If untreated, it can cause serious complications, affecting quality of life and mobility.

 

Diabetic Neuropathy Diagnosis:

Diagnosis of diabetic neuropathy involves a combination of patient history, physical examination, and specialized tests. Common methods include nerve conduction studies, electromyography (EMG), and quantitative sensory testing to assess nerve function. Blood tests and screening for other causes are also conducted to confirm the diagnosis and rule out other conditions.

 

Diabetic Neuropathy Treatment:

Treatment of diabetic neuropathy focuses on managing symptoms and slowing disease progression. It includes blood sugar control, pain relief using medications like anticonvulsants, antidepressants, and topical agents, as well as lifestyle changes. Physical therapy and supportive care help improve mobility and quality of life for affected patients.

 

Diabetic Neuropathy Treatment Epidemiology

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by Total Diagnosed Incident Population of Diabetic Neuropathy Treatment, Gender-specific Diagnosed Incidence of Diabetic Neuropathy Treatment, Type-specific Diagnosed Incidence of Diabetic Neuropathy Treatment, Age-specific Diagnosed Incidence of Diabetic Neuropathy Treatment, Diagnosed Incident Population based on Primary Site of Diabetic Neuropathy Treatment, and Diagnosed Incident Population based on Histologic Classification of Diabetic Neuropathy Treatment Tumour in the global market covering North America, Europe, Asia-Pacific, Latin America, the Middle East, and Africa from 2024 to 2035.

 

Principal Insights

This section offers a global overview of diabetic neuropathy treatment epidemiology in major markets worldwide.

 

Country Wise- Diabetic Neuropathy Treatment Multiforme Epidemiology

  • The epidemiology segment provides Diabetic Neuropathy Treatment prevalence data and findings across key regions worldwide, including North America, Europe (Germany, France, Italy, Spain, and the United Kingdom), Asia-Pacific (including Japan), Latin America, the Middle East, and Africa.

 

Diabetic Neuropathy Treatment: Recent Developments:

  • In January 2022, Medtronic announced FDA approval of its Intellis and Vanta spinal cord stimulators for treating chronic pain from Diabetic Neuropathy. The devices were indicated to significantly reduce pain-70% of patients experienced relief, and 53% average pain reduction, offering rechargeable and recharge-free therapy options with unrestricted MRI access.

 

 

Diabetic Neuropathy Treatment Marketed Drugs:

  • Lyrica: Pfizer Inc.

Lyrica (pregabalin) is an FDA-approved anticonvulsant used to treat neuropathic pain associated with diabetic neuropathy. It works by reducing nerve signal transmission, helping to decrease pain and discomfort in affected patients.

 

  • Cymbalta: Eli Lilly and Company

Cymbalta (duloxetine) is an FDA-approved serotonin-norepinephrine reuptake inhibitor (SNRI) indicated for managing diabetic neuropathic pain. It modulates neurotransmitters to alleviate pain and improve patient's quality of life.

 

 

Diabetic Neuropathy Treatment: Emerging Therapies

 

VX-548: It is an oral NaV1.8 channel inhibitor in late-stage clinical trials for Diabetic Neuropathy Treatment. It selectively targets peripheral nerve sodium channels to reduce pain signaling, aiming to offer a non-opioid treatment option with a favourable safety profile for chronic neuropathic pain.

 

LX9211: It is a small molecule AAK1 inhibitor under investigation for painful Diabetic Neuropathy Treatment. It modulates neuronal signaling involved in chronic pain and has shown significant efficacy in Phase II trials, potentially offering a new, non-opioid approach to managing neuropathic symptoms.

 

VM202: It is a plasmid-based gene therapy encoding hepatocyte growth factor (HGF) in Phase III trials for Diabetic Neuropathy Treatment. It aims to regenerate damaged nerves and relieve pain by promoting angiogenesis and neuroprotection, representing a novel regenerative approach to neuropathy treatment.

 

SGT-601: It is an investigational therapy targeting pain receptor modulation in diabetic nerve damage. It is designed to block specific pain pathways without affecting normal sensory functions, aiming to provide effective pain relief with minimal side effects in ongoing early-stage trials.

 

 

Diabetic Neuropathy Treatment Market Outlook

  • The Diabetic Neuropathy Treatment market focuses on the diagnosis, treatment, and management of nerve damage caused by diabetes. It includes a wide range of pharmaceuticals, devices, and therapeutic solutions aimed at relieving pain, improving nerve function, and enhancing patient quality of life.
  • The market is driven by the growing global diabetic population, increased awareness of diabetic complications, and the rising demand for effective pain management solutions. Advancements in diagnostic tools, treatment innovations, and increased investment in R&D further propel the market’s steady growth.
  • Opportunities lie in the development of non-opioid therapies, expansion into emerging markets, and integration of digital health technologies. Growth in personalized medicine and gene therapies also presents significant potential for targeting underlying causes and improving treatment outcomes in diabetic neuropathy.
  • Governments support the diabetic neuropathy market through funding for chronic disease programs, encouraging R&D in pain management, expanding healthcare coverage, and supporting public awareness campaigns. These initiatives aim to reduce disease burden and improve access to treatment for affected populations.
  • Limited efficacy and side effects of current therapies remain major challenges in treating diabetic neuropathy.
  • The market is expected to grow steadily due to rising diabetes prevalence and increasing demand for more effective and safer neuropathic pain treatments.

 

 

Diabetic Neuropathy Treatment Market Segmentation

By Disorder Type:

  • Peripheral Neuropathy
  • Autonomic Neuropathy
  • Proximal Neuropathy
  • Focal Neuropathy

 

 

Peripheral neuropathy holds the largest share in the market due to its high prevalence among diabetic patients. It commonly presents as numbness, tingling, and pain in extremities, prompting early diagnosis and ongoing treatment. Its widespread occurrence drives consistent demand for therapeutic management and diagnostic monitoring.

 

By Drug Class:

  • NSAIDs
  • Capsaicin
  • Opioid
  • Antidepressants
  • Others

 

Antidepressants dominate the drug class segment as they are commonly prescribed for neuropathic pain management in diabetic patients. These medications, particularly SNRIs and TCAs, effectively relieve chronic nerve pain, making them a mainstay in treatment protocols. Their dual action on mood and pain enhances patient outcomes.

 

Regional Segment Analysis of the Diabetic Neuropathy Treatment Market

 

North America holds the largest share in the Diabetic Neuropathy Treatment market due to its high diabetic population, advanced healthcare infrastructure, and widespread access to diagnostic and therapeutic services. The presence of major pharmaceutical companies, strong reimbursement frameworks, and increased awareness about diabetic complications contribute to market dominance. Ongoing clinical research and product development further support consistent growth and patient adoption of newer treatment options.

 

Asia-Pacific is the fastest-growing region in the Diabetic Neuropathy Treatment market, driven by rising diabetes prevalence, improving healthcare access, and increasing investments in medical infrastructure. Growing awareness among patients, supportive government health initiatives, and a large underserved population contribute to expanding treatment demand. Pharmaceutical companies are also targeting this region with strategic collaborations and affordable drug options to capture emerging market potential.

 

Diabetic Neuropathy Treatment Market Key Companies

  • Pfizer Inc.
  • Eli Lilly and Company
  • GlaxoSmithKline plc
  • Novartis AG
  • Teva Pharmaceutical Industries Ltd.
  • Abbott Laboratories
  • Janssen Pharmaceuticals
  • NeuroMetrix Inc.
  • Astellas Pharma Inc.
  • Boehringer Ingelheim
  • Sanofi S.A.
  • Daiichi Sankyo Company Ltd.
  • UCB Pharma
  • Grunenthal GmbH
  • Vertex Pharmaceuticals
  • Others

 

Diabetic Neuropathy Therapeutics Market Report Scope

  • The Diabetic Neuropathy therapeutics market report provides a detailed overview, covering its causes, symptoms, disease progression, and existing treatment options.
  • Detailed insights into Diabetic Neuropathy Treatment’s epidemiology and therapeutic approaches are included.
  • Additionally, a comprehensive review of existing and emerging Diabetic Neuropathy Treatment therapies is provided, including an evaluation of new treatments expected to influence the current Diabetic Neuropathy Treatment market landscape.
  • The report includes a detailed review of the Diabetic Neuropathy therapeutics market, both historical and forecasted, highlighting the global drug reach.
  • The Patient-Based Diabetic Neuropathy Treatment Market Forecasting report offers valuable insights into trends shaping the global Diabetic Neuropathy Treatment market, helping to develop effective business strategies.

 

Diabetic Neuropathy Treatment Market Report Insights

  • Forecasting Market Trends Based on Patient Data and Disease Rates
  • Diabetic Neuropathy Therapeutic Approaches in Diabetic Neuropathy Treatment
  • Review Of Drugs in Development for Diabetic Neuropathy Treatment
  • Market, Growth, and Trends in Diabetic Neuropathy Treatment
  • Market Opportunities in Diabetic Neuropathy Treatment
  • Effects Of Future Therapies on Diabetic Neuropathy Treatment.

 

Diabetic Neuropathy Treatment Market Report Key Strengths

  • 15 Years Diabetic Neuropathy Treatment Market Forecast
  • Global Coverage
  • Diabetic Neuropathy Treatment Epidemiology Segmentation
  • Key Cross Competition

 

Diabetic Neuropathy Treatment Market Report Assessment

  • Present Practices in the Diabetic Neuropathy Treatment Market
  • Review of Investigational Diabetic Neuropathy Treatment Drugs
  • Attractiveness of the Diabetic Neuropathy Treatment Drug Market
  • Diabetic Neuropathy Treatment Market Drivers
  • Diabetic Neuropathy Treatment Market Barriers
  • SWOT
  • Attribute Analysis

 

Market Segment

This study forecasts revenue at the global, regional, and country levels from 2020 to 2035. Spherical Insights has segmented the diabetic neuropathy treatment market based on the below-mentioned segments:

 

Global Diabetic Neuropathy Treatment Market, By Disorder Type

  • Peripheral Neuropathy
  • Autonomic Neuropathy
  • Proximal Neuropathy
  • Focal Neuropathy

 

Global Diabetic Neuropathy Treatment Market, By Drug Class

  • NSAIDs
  • Capsaicin
  • Opioid
  • Antidepressants
  • Others

 

Global Diabetic Neuropathy Treatment Market, By Regional Analysis

  • North America
    • US
    • Canada
    • Mexico
  • Europe
    • Germany
    • UK
    • France
    • Italy
    • Spain
    • Russia
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Australia
    • Rest of Asia Pacific
  • South America
    • Brazil
    • Argentina
    • Rest of South America
  • Middle East & Africa
    • UAE
    • Saudi Arabia
    • Qatar
    • South Africa
    • Rest of the Middle East & Africa

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