Global Spinal Allografts Market Size, Share, and COVID-19 Impact Analysis, By Surgery Type (Open Spine Surgery and Minimally Invasive Spine Surgery), By Product Type (Machined Bone Allografts and Demineralized Bone Matrix), By End User (Hospitals, Ambulatory Surgical Centers, and Others), and By Region (North America, Europe, Asia-Pacific, Latin America, Middle East, and Africa), Analysis and Forecast 2025 - 2035

Global Spinal Allografts Market Insights Forecasts to 2035

• The Global Spinal Allografts Market Size Was Estimated at USD 3.65 Billion in 2024
• The Market Size is Expected to Grow at a CAGR of around 9.34% from 2025 to 2035
• The Worldwide Spinal Allografts Market Size is Expected to Reach USD 9.75 Billion by 2035
• Asia Pacific is Expected to Grow the fastest during the forecast period.

The Global Spinal Allografts Market Size was Worth around USD 3.65 Billion in 2024 and is predicted to Grow to around USD 9.75 Billion by 2035 with a compound annual growth rate (CAGR) of 9.34% from 2025 to 2035. The growing prevalence of spinal disorders, the demand for minimally invasive spine surgeries, and advancements in tissue processing techniques are driving the global spinal allografts market.  

Market Overview

The Spinal Allografts Market Size is the market encompassing the supply and distribution of bone or tissue grafts, derived from human donors (allografts), used in spinal fusion surgeries to promote bone growth and fusion. Bone allografts are commonly used in spinal surgery procedures, including spinal fusion, disc replacement, and vertebral reconstruction. It encompasses cadaveric cancellous bone, cadaveric cortical bone, demineralized bone matrix, and allografts containing mesenchymal stem cells. The ability of allografts to reduce donor site morbidity, eliminating the need for autograft harvesting, with minimum operation time, is driving the demand for spinal allografts. Advancements in surgical instrumentation and minimally invasive techniques facilitate more precise placement and use of allografts. Ongoing research on methods for enhancing the graft quality by the development of novel sterilization techniques, as well as the use of gene therapy and 3D printed grafts for enhancing graft performance, is offering lucrative market growth opportunities. Further, collaborations among surgeons, researchers, and industry leaders are driving innovation in allograft technology in order to improve patient outcomes.

Report Coverage

This research report categorizes the spinal allografts market based on various segments and regions, forecasts revenue growth, and analyzes trends in each submarket. The report analyses the key growth drivers, opportunities, and challenges influencing the spinal allografts market. Recent market developments and competitive strategies such as expansion, type launch, development, partnership, merger, and acquisition have been included to draw the competitive landscape in the market. The report strategically identifies and profiles the key market players and analyses their core competencies in each sub-segment of the spinal allografts market.

Driving Factors

The growing prevalence of spinal disorders, most commonly affecting the lumbar and cervical spine, is anticipated to drive the market. The increasing demand for minimally invasive spine surgeries due to shorter recovery times and reduced postoperative pain is contributing to promoting the spinal allografts market. Ongoing development on new proprietary techniques for allograft processing and sterilization is propelling the market growth. The use of allografts eliminates the need for additional surgical procedures, thus eliminating the risk of infection, which is a positive factor for market growth.

Restraining Factors

The concerns related to disease transmission and immune reactions may limit its adoption, thereby restricting the market. Further, the stringent regulatory policies and lack of reimbursement policies are restraining the market growth.

Market Segmentation

The spinal allografts market share is classified into surgery type, product type, and end user.

• The open spine surgery segment dominated the market with the largest revenue share in 2024 and is projected to grow at a substantial CAGR during the forecast period.

Based on the surgery type, the spinal allografts market is divided into open spine surgery and minimally invasive spine surgery. Among these, the open spine surgery segment dominated the market with the largest revenue share in 2024 and is projected to grow at a substantial CAGR during the forecast period. Open spine surgery is a traditional approach in which a large incision is made that allows direct access to the spine for thorough examination of the affected area. In complex spinal conditions in which extensive grafting and structural support are needed, a spinal allograft is used.

• The demineralized bone matrix segment accounted for the largest market share in 2024 and is anticipated to grow at a significant CAGR during the forecast period.

Based on the product type, the spinal allografts market is divided into machined bone allografts and demineralized bone matrix. Among these, the demineralized bone matrix segment accounted for the largest market share in 2024 and is anticipated to grow at a significant CAGR during the forecast period. Demineralized bone matrix is prepared by pulverization of allogenic bone to a consistent size, followed by mild acid extraction of the mineralized phase of bone. Demineralized bone matrix has high clinical applicability in spinal fusion procedures and is used in combination with autografts or other scaffolding materials.

• The hospitals segment dominated the spinal allografts market in 2024 and is anticipated to grow at a significant CAGR during the forecast period.

Based on the end user, the spinal allografts market is divided into hospitals, ambulatory surgical centers, and others. Among these, the hospitals segment dominated the spinal allografts market in 2024 and is anticipated to grow at a significant CAGR during the forecast period. It was estimated that more than 650,000 spinal fusion surgeries are performed annually. An increasing need for improved graft materials, with the growing number of spinal fusion surgeries, is contributing to driving the market in the hospitals segment.

Regional Segment Analysis of the Spinal Allografts Market

• North America (U.S., Canada, Mexico) 
• Europe (Germany, France, U.K., Italy, Spain, Rest of Europe)
• Asia-Pacific (China, Japan, India, Rest of APAC)
• South America (Brazil and the Rest of South America) 
• The Middle East and Africa (UAE, South Africa, Rest of MEA)

North America is anticipated to hold the largest share of the spinal allografts market over the predicted timeframe.

North America is anticipated to hold the largest share of the spinal allografts market over the predicted timeframe. The presence of robust healthcare infrastructure, along with the growing innovation in grafting products, is driving the spinal allografts market. Further, the strong adoption of spinal biologics among U.S. surgeons and healthcare providers aids in propelling the market of spinal allografts. 

Asia Pacific is expected to grow at a rapid CAGR in the spinal allografts market during the forecast period. An increasing awareness about spinal disorders and biologics in the region is responsible for driving the spinal allografts market. The growing aging population is also responsible for market demand, as the aging demographic is more susceptible to spinal injuries, disc degeneration, and osteoporosis-related deformities.

Europe is anticipated to grow at a substantial CAGR in the spinal allografts market during the predicted timeframe. The regions well-established medical device market, along with the increased patient awareness, is contributing to driving the spinal allografts market. The growing prevalence of spinal issues, along with the increasing number of less invasive operations, is contributing to market growth of spinal allografts.

Competitive Analysis:

The report offers the appropriate analysis of the key organizations/companies involved within the spinal allografts market, along with a comparative evaluation primarily based on their type of offering, business overviews, geographic presence, enterprise strategies, segment market share, and SWOT analysis. The report also provides an elaborative analysis focusing on the current news and developments of the companies, which includes type development, innovations, joint ventures, partnerships, mergers & acquisitions, strategic alliances, and others. This allows for the evaluation of the overall competition within the market.

List of Key Companies

• Medtronic
• Stryker
• Zimmer Biomet
• NuVasive, Inc.
• RTI Surgical Holdings, Inc.
• LifeNet Health
• Seaspine Holdings Corporation
• Allosource, Inc.
• Johnson & Johnson
• Smith plus Nephew
• Orthofix Medical Inc.
• MTF Biologics
• Xtant Medical Holdings, Inc.
• Integra LifeSciences Holdings Corporation (U.S.)
• Globus Medical, Inc.
• Others

Key Target Audience

• Market Players
• Investors
• End-users
• Government Authorities 
• Consulting And Research Firm
• Venture capitalists
• Value-Added Resellers (VARs) 

Recent Development

• In April 2023, MTF Biologics, a leading nonprofit organization dedicated to providing high-quality allografts, announced the launch of a next-generation machined bone allograft designed to support complex spinal fusion procedures.

• In June 2018, RTI Surgical, Inc., a global surgical implant company, announced the full commercial launch of its Fortilink-TS and -L IBF Systems, adding to a growing series of interbody fusion devices featuring proprietary TETRAfuse 3D technology.

Market Segment

This study forecasts revenue at global, regional, and country levels from 2020 to 2035. Spherical Insights has segmented the spinal allografts market based on the below-mentioned segments: 

Global Spinal Allografts Market, By Surgery Type

• Open Spine Surgery
• Minimally Invasive Spine Surgery

Global Spinal Allografts Market, By Product Type

• Machined Bone Allografts
• Demineralized Bone Matrix

Global Spinal Allografts Market, By End User

• Hospitals
• Ambulatory Surgical Centers
• Others

Global Spinal Allografts Market, By Regional Analysis

• North America
  • US
  • Canada
  • Mexico
• Europe
  • Germany
  • UK
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Rest of Asia Pacific
• South America
  • Brazil
  • Argentina
  • Rest of South America
• Middle East & Africa
  • UAE
  • Saudi Arabia
  • Qatar
  • South Africa
  • Rest of the Middle East & Africa