Japan Organ Preservation Market Size, Share, and COVID-19 Impact Analysis, By Preservation Solution (UW Solution, Custodiol HTK, Perfadex, and Others), By Technique (Static Cold Storage Technique, Hypothermic Machine Perfusion, Normothermic Machine Perfusion, and Others), By Organ Type (Kidney, Liver, Lung, Heart, and Others), and Japan Organ Preservation Market Insights, Industry Trend, Forecasts to 2035

Japan Organ Preservation Market Insights Forecasts to 2035

• The Japan Organ Preservation Market Size Was Estimated at USD 3.28 Million in 2024
• The Market Size is Expected to Grow at a CAGR of Around 6.11% from 2025 to 2035
• The Japan Organ Preservation Market Size is Expected to Reach USD 6.30 Million by 2035

According to a research report published by Spherical Insights & Consulting, the Japan organ preservation market size is anticipated to reach USD 6.30 million by 2035, growing at a CAGR of 6.11% from 2025 to 2035. The organ preservation market in Japan is driven by the rising demand for organ preservation brought on by the rising number of organ transplants, as well as the need for efficient organ preservation techniques to improve organ viability, raise transplant success rates, and broaden the pool of available organs.

Market Overview

Organ preservation is the method of maintaining organs external to the body until they can be transplanted into a recipient or be used for research purposes, which requires specific techniques to maintain organs as viable and functional for study. The organ preservation method tries to mitigate injury by decreasing oxygen and nutrient delivery when the organ is cold, and through metabolic processes, like inflammation, and irreversible damage to organ tissues. The Japanese organ preservation market is experiencing a steady increase, driven by rising cases of organ failure in need of transplantation and new developments in organ preservation. In particular, there have been significant government-led initiatives to enhance the donation and organ preservation systems, including the enactment of the revised Organ Transplant Law in 2010, attempts to build public awareness, and investments and efforts to enhance infrastructure for transplanting organs. Technological developments such as hypothermic and normothermic machine perfusion for organ graft preservation, new solutions for organ perfusion, and Artificial Intelligence (AI) tools for viability assessment have begun to improve the success of organ grafting. Future commercial opportunities lie in machine perfusion practices, developing bioengineered organs, and integrating electronic logistics and AI into organ transport and utilization throughout Japan.

Report Coverage

This research report categorizes the market for the Japan organ preservation market based on various segments and regions, and forecasts revenue growth and analyzes trends in each submarket. The report analyses the key growth drivers, opportunities, and challenges influencing the Japan organ preservation market. Recent market developments and competitive strategies, such as expansion, product launch, development, partnership, merger, and acquisition, have been included to draw the competitive landscape in the market. The report strategically identifies and profiles the key market players and analyzes their core competencies in each sub-segment of the Japan organ preservation market.

Driving Factors

The organ preservation market in Japan is driven by the increasing incidence of end-stage organ failure, particularly of the kidneys and liver, which drives demand for treatment through transplantation and preservation. The support of government policies and regulatory reforms to the Organ Transplant Law, along with education regarding donor registration and public awareness of organ transplantation, helps to grow the market. Developments in preservation technology, including hypothermic and normothermic machine perfusion, preservation solutions, and artificial intelligence for organ viability assessment, can lead to improved outcomes for organ transplant recipients. In addition, the growth of the aging population, the increase in the number of medical institutions focused on transplant and transplantation education, and continued innovation by medical device manufacturers add to the growth of the organ preservation market in Japan.

Restraining Factors

The organ preservation market in Japan is mostly constrained by low donation rates, especially among deceased donors, which limits transplantation volume and decreases the need for advanced preservation solutions. The high costs of machine perfusion (MP) devices and specialized solutions limited their overall uptake, particularly in smaller hospitals. Furthermore, highly regulated and influenced ethical considerations around organ procurement are additional constraints to market growth.

Market Segmentation

The Japan organ preservation market share is classified into preservation solutions, techniques, and organ types.

• The UW Solution segment accounted for the largest revenue market share in 2024 and is expected to grow at a significant CAGR during the forecast period. 

The Japan organ preservation market is segmented by preservation solutions into UW Solution, Custodiol HTK, Perfadex, and others. Among these, the UW Solution segment accounted for the largest revenue market share in 2024 and is expected to grow at a significant CAGR during the forecast period. The UW Solution is seen as the gold standard in organ preservation, especially for liver, kidney, and pancreas transplantations. The UW solution provides enhanced protection against ischemic injury by preserving cell membrane integrity with a reduction in metabolic degradation during cold storage. Because of its clinical efficacy, widespread use among many Japanese transplant centers, and the fact that it works with various organs, it is the preferred solution.

• The static cold storage technique segment accounted for the largest revenue share in 2024 and is expected to grow at a significant CAGR during the forecast period. 

The Japan organ preservation market is segmented by techniques into static cold storage technique, hypothermic machine perfusion, normothermic machine perfusion, and others. Among these, the static cold storage technique segment accounted for the largest revenue share in 2024 and is expected to grow at a significant CAGR during the forecast period. The static cold storage method is still the most common method due to its cost-effectiveness, simplicity, and proven track record for the preservation of organs such as kidneys, livers, and hearts for short time intervals. This is a low-tech approach requiring minimal equipment and infrastructure to maintain a steel drum, making it appropriate for hospitals and transplant centers throughout Japan.

• The kidney segment accounted for the largest revenue share in 2024 and is expected to grow at a significant CAGR during the forecast period. 

The Japan organ preservation market is segmented by organ type into kidney, liver, lung, heart, and others. Among these, the kidney segment accounted for the largest revenue share in 2024 and is expected to grow at a significant CAGR during the forecast period. In Japan, kidney transplants are the most common type of organ transplantation, due to the high rates of chronic kidney disease (CKD) and end-stage renal failure (ESRF). The number of patients on dialysis and the awareness of the effects of transplantation are also increasing the need for kidney preservation.

Competitive Analysis:

The report offers the appropriate analysis of the key organizations/companies involved within the Japan organ preservation market, along with a comparative evaluation primarily based on their product offering, business overviews, geographic presence, enterprise strategies, segment market share, and SWOT analysis. The report also provides an elaborate analysis focusing on the current news and developments of the companies, which includes product development, innovations, joint ventures, partnerships, mergers & acquisitions, strategic alliances, and others. This allows for the evaluation of the overall competition within the market.

List of Key Companies

• Terumo Corporation
• Nipro Corporation
• Japan Tissue Engineering Co., Ltd. (J-TEC)
• PorMedTec
• Heartseed Inc.
• Asahi Kasei Corporation
• Fujirebio Holdings, Inc.
• Takeda Pharmaceutical Company
• SanBio Co., Ltd.
• Others

Key Target Audience

• Market Players
• Investors
• End-users
• Government Authorities 
• Consulting and Research Firm
• Venture capitalists
• Value-Added Resellers (VARs)

Recent Developments:

• In August 2023, a multicentre clinical trial using hypothermic machine perfusion (HMP), in kidney transplantation from marginal donors (both donation after brain death and donation after circulatory death) was initiated in Japan with a domestic perfusion device.

Market Segment

This study forecasts revenue at the Japan, regional, and country levels from 2020 to 2035. Spherical Insights has segmented the Japan organ preservation market based on the below-mentioned segments:

Japan Organ Preservation Market, By Preservative Solution

• UW Solution
• Custodiol HTK
• Perfadex
• Others

Japan Organ Preservation Market, By Technique

• Static Cold Storage Technique
• Hypothermic Machine Perfusion
• Normothermic Machine Perfusion
• Others

Japan Organ Preservation Market, By Organ Type

• Kidney
• Liver
• Lung
• Heart
• Others