Japan Oligonucleotide Synthesis Market Size, Share, By Product (Synthesized Oligonucleotide Products, Reagents, Equipment, and Services), By Application (PCR Primers, PCR Assays and Panels, Sequencing, DNA Microarrays, Fluorescence In-Situ Hybridization, Antisense Oligonucleotides, and Others), By End Use (Pharmaceutical and Biotechnology Companies, Hospital and Diagnostic Laboratories and Academic Research Institutes) Japan Oligonucleotide Synthesis Market Size Industry Trend, Forecasts to 2035

Japan Oligonucleotide Synthesis Market Size Insights Forecasts to 2035

• Japan Oligonucleotide Synthesis Market Size 2024: USD 204.22 Million
• Japan Oligonucleotide Synthesis Market Size 2035:  USD 748.12 Million
• Japan Oligonucleotide Synthesis Market Size CAGR 2024: 12.53%
• Japan Oligonucleotide Synthesis Market Size Segments: Product, Applications, and End Use. 

The Japan Oligonucleotide Synthesis Market Size is an oligonucleotide-based product research, diagnosis, therapy, and commercialisation industry. The oligonucleotide is a DNA or RNA chain consisting of only a few nucleotides found in genes. It plays a significant role in medicine, PCR, antisense therapy, etc. The Japan Oligonucleotide Synthesis Market Size provides goods to a variety of industries, including pharmaceutical companies, biotechnology companies, research organisations, and academic research institutes. Furthermore, Japan Oligonucleotide Synthesis Market Size growth is driven by increasing demand for personalised medicine, targeted therapies, and gene-based treatments. Rising investment in genomics and molecular biology research, expanding biopharmaceutical development, and growing adoption of nucleic acid-based diagnostics support the market. Technological advancements in synthesis methods and higher R&D funding from private and public sectors also contribute to the expansion of oligonucleotide applications.

The support of the Japan government towards the development of biotechnology and genomic research is evident through the funding programs, regulations, or initiatives taken for the development of health innovation in the country. The development of nucleic acid-based therapies is encouraged under the policies of the Ministry of Health, Labour, and Welfare (MHLW). The quality, safety, and clinical trials ensure the reliability.

Trends in the Japan Oligonucleotide Synthesis Market Size include an upward trend in the adoption of automated or high-throughput oligonucleotide synthesis technologies, the continued growth of antisense oligonucleotides (ASOs), and a steady increase in the number of applications for RNA-based therapeutics and CRISPR gene editing. There is also a continued emphasis on personalised medicine, particularly with respect to cancer treatment and vaccine development.

Market Dynamics of the Japan Oligonucleotide Synthesis Market Size:

The Japan Oligonucleotide Synthesis Market Size is drivers of Japan's Oligonucleotide Synthesis Market Size Include factors driving the Japan oligonucleotide synthesis industry are an increase in the incidence of genetic disorders/chronic diseases, increased R&D spending on biopharmaceuticals, and advances in synthetic biology. Additionally, the requirement for highly precise and efficient production of oligonucleotides, whether for diagnostic uses, vaccine development, or genetic therapies, is contributing to the overall growth of the market.

The Japan Oligonucleotide Synthesis Market Size is facing several restraining factors, including high production and operational costs, complex synthesis and purification processes, and challenges in achieving large-scale, high-purity output. Strict regulatory requirements, a limited skilled workforce, long development timelines, and intellectual property concerns further hinder growth. Competition from established global manufacturers and integration difficulties with advanced technologies also slow market expansion.

The Japan Oligonucleotide Synthesis Market Size offers Opportunities lie in personalised medicine, RNA therapeutics, antisense and siRNA drug development, and CRISPR-based applications. Expansion into vaccine development, oncology, and rare disease therapeutics presents growth potential. Adoption of automated, high-throughput synthesis platforms and collaborations with global biotech firms can enhance market reach. Increasing demand for high-purity, scalable oligonucleotides offers opportunities for manufacturers and service providers.

Market Segmentation

The Japan Oligonucleotide Synthesis Market Size share is classified into product, applications, and end use.

By Product:

The Japan Oligonucleotide Synthesis Market Size is divided by product into synthesised oligonucleotide products, reagents, equipment, and services. Among these, the synthesised oligonucleotide products segment dominated the share in 2024 and is anticipated to grow at a remarkable CAGR during the forecast period. The synthesised oligonucleotide products segment dominates because these products are essential for research, diagnostics, and therapeutics. High demand from pharmaceutical, biotechnology, and academic sectors ensures consistent usage, surpassing the need for reagents, equipment, or services.

By Application:

The Japan Oligonucleotide Synthesis Market Size is divided by application into pcr primers, pcr assays and panels, sequencing, DNA microarrays, fluorescence in situ hybridisation, antisense oligonucleotides, and others. Among these, the pcr primers segment dominated the share in 2024 and is anticipated to grow at a remarkable CAGR during the forecast period. The PCR primers segment dominates because they are essential for gene amplification, diagnostics, and molecular research. High demand from laboratories, pharmaceutical companies, and academic institutions drives consistent consumption, surpassing other applications like sequencing or antisense therapies.

By End Use:

The Japan Oligonucleotide Synthesis Market Size is divided by end use into pharmaceutical and biotechnology companies, hospital and diagnostic laboratories and academic research institutes. Among these, the pharmaceutical and biotechnology companies segment dominated the share in 2024 and is anticipated to grow at a remarkable CAGR during the forecast period. The pharmaceutical and biotechnology companies segment dominates because they require large-scale, high-purity oligonucleotides for drug discovery, RNA-based therapies, gene editing, and molecular research, resulting in higher consumption than hospitals, diagnostic laboratories, or academic research institutes.

Competitive Analysis:

The report offers the appropriate analysis of the key organisations/companies involved within the Japan Oligonucleotide Synthesis Market Size, along with a comparative evaluation primarily based on their product offering, business overviews, geographic presence, enterprise strategies, segment market share, and SWOT analysis. The report also provides an elaborate analysis focusing on the current news and developments of the companies, which includes product development, innovations, joint ventures, partnerships, mergers & acquisitions, strategic alliances, and others. This allows for the evaluation of the overall competition within the market. 

Top Key Companies in Japan Oligonucleotide Synthesis Market Size:

• Thermo Fisher Scientific Inc.
• Agilent Technologies, Inc.
• Bachem
• ST Pharm
• Kaneka Eurogentec S.A.
• Ajinomoto Co., Inc. (with Gene Design, Inc.)
• Eurofins Scientific / Eurofins Genomics.
• Gen Script.
• Merck KGaA.
• Integrated DNA Technologies (IDT)
• Others

Key Target Audience

• Market Players
• Investors
• End-users
• Government Authorities 
• Consulting and Research Firm
• Venture capitalists
• Value-Added Resellers (VARs)

Market Segment

This study forecasts revenue at the Japan, regional, and country levels from 2020 to 2035. Spherical Insights has segmented the Japan Oligonucleotide Synthesis Market Size based on the below-mentioned segments:

Japan Oligonucleotide Synthesis Market Size, By Product.

• Synthesised Oligonucleotide Products
• Reagents
• Equipment
• Services

Japan Oligonucleotide Synthesis Market Size, By Application

• Pcr Primers
• Pcr Assays and Panels
• Sequencing
• DNA Microarrays
• Fluorescence In-Situ Hybridisation,
• Antisense Oligonucleotides
• Others

Japan Oligonucleotide Synthesis Market Size, By End Use.

• Pharmaceutical and Biotechnology Companies
• Hospital and Diagnostic Laboratories
• Academic Research Institutes