Global Glyoxylic Acid Market Size, Share, and COVID-19 Impact Analysis, By Derivative (Allantoin, Vanillin, P-Hydroxyphenylglycine, DL-P-Hydroxyphenyl Hydantoin, 2-Hydroxyl-Phosphine Acetic Acid, and Others), By Application (Personal Care & Cosmetics Ingredients, Pharmaceutical, Aromas, Agrochemicals, and Others), and By Region (North America, Europe, Asia-Pacific, Latin America, Middle East, and Africa), Analysis and Forecast 2025 - 2035

Global Glyoxylic Acid Market Insights Forecasts to 2035

• The Global Glyoxylic Acid Market Size Was Estimated at USD 0.68 Billion in 2024
• The Market Size is Expected to Grow at a CAGR of around 4.64% from 2025 to 2035
• The Worldwide Glyoxylic Acid Market Size is Expected to Reach USD 1.12 Billion by 2035
• North America is expected to grow the fastest during the forecast period.

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According to a research report published by Spherical Insights and Consulting, The global glyoxylic acid market size was worth around USD 0.68 Billion in 2024, growing to USD 0.71 Billion in 2025, and is predicted to grow to around USD 1.12 Billion by 2035 with a compound annual growth rate (CAGR) of 4.64% from 2025 to 2035. The market for glyoxylic acid presents substantial opportunities due to its increasing use in cosmetics, agrochemicals, and medicines. Market expansion is also fueled by growing awareness of eco-friendly products and applications in sustainable manufacturing.

 

Global Glyoxylic Acid Market Forecast and Revenue Size

• 2024 Market Size: USD 0.68 Billion
• 2025 Market Size: USD 0.71 Billion
• 2035 Projected Market Size: USD 1.12 Billion
• CAGR (2025-2035): 4.64%
• Asia Pacific: Largest market in 2024
• North America: Fastest growing market

 

Market Overview    

The global glyoxylic acid market refers to the international trade and consumption of glyoxylic acid, a versatile organic compound used as an intermediate in various chemical processes. The global glyoxylic acid market is undergoing a significant transformation, driven by advancements in chemical synthesis and rising demand across personal care, pharmaceutical, and agrochemical sectors. Countries like China, India, and the United States are leading production and consumption due to expanding industrial applications. Government initiatives promoting sustainable chemical manufacturing are shaping market dynamics globally. In China, rapid industrialization and favorable regulatory frameworks are boosting glyoxylic acid output. India is witnessing increased demand for cosmetic and aroma-based derivatives, fueling market growth. The United States continues to invest in R&D for bio-based alternatives, influencing global innovation trends. The global glyoxylic acid market is experiencing notable trends driven by rising demand in personal care, pharmaceutical, and agrochemical sectors. 

 

Key Market Insights

• Asia Pacific is expected to account for the largest share in the glyoxylic acid market during the forecast period.     

 

• In terms of derivatives, the allantoin segment is projected to lead the glyoxylic acid market throughout the forecast period   

 

• In terms of application, the personal care & cosmetics ingredients segment captured the largest portion of the market       

 

Glyoxylic Acid Market Trends

• Sustainable Production: To comply with environmental standards, manufacturers are using eco-friendly procedures, such as using energy-efficient methods and renewable raw materials.

 

• Technological Advancements: Production efficiency and cost-effectiveness are being improved by higher yields and improvements in catalytic processes.

 

• Strategic Partnerships: To increase market reach and guarantee a steady supply chain, businesses are establishing alliances and joint ventures.

 

• Investment Opportunities: Chemical makers and distributors have strategic investment opportunities due to the market's expansion and the demand for unique ingredients.

 

Report Coverage  

This research report categorizes the glyoxylic acid market based on various segments and regions, forecasts revenue growth, and analyzes trends in each submarket. The report analyzes the key growth drivers, opportunities, and challenges influencing the glyoxylic acid market. Recent market developments and competitive strategies, such as expansion, product launch, development, partnership, merger, and acquisition, have been included to draw the competitive landscape in the market. The report strategically identifies and profiles the key market players and analyzes their core competencies in each sub-segment of the glyoxylic acid market.       

 

Driving factors:  

The global glyoxylic acid market is expanding steadily, driven by technological advancements and rising consumer demand across key regions like China, India, and the United States. China leads in production capacity due to its robust chemical manufacturing infrastructure and favorable government policies. India is witnessing increased demand for glyoxylic acid in personal care and pharmaceutical applications, supported by digital retail growth and evolving consumer preferences. The United States is investing in sustainable and bio-based chemical technologies, further propelling glyoxylic acid market. These factors collectively contribute to the dynamic growth of the glyoxylic acid market across China, India, and the United States. Increasing consumer preference for natural and bio-based ingredients is pushing manufacturers toward sustainable production methods. 

 

Restraining Factors:  

The global glyoxylic acid market faces restraints such as high production costs and strict environmental regulations, especially in developed regions. Limited availability of raw materials can disrupt supply chains and affect pricing stability. Additionally, competition from alternative chemical intermediates may hinder market expansion.  

 

Market Segmentation     

The global glyoxylic acid market is divided into derivatives and application.

 

Global Glyoxylic Acid Market, By Derivative:    

What makes allantoin a common ingredient in skincare products?

The allantoin segment led the glyoxylic acid market, generating the largest revenue share. Allantoin is a common ingredient in skincare products because of its relaxing, hydrating, and healing properties. As a keratolytic agent, it promotes skin cell regeneration while softening and eliminating dead skin cells. In order to treat dry, irritated, or injured skin, such as eczema, psoriasis, and sunburn, allantoin is commonly used in creams, lotions, ointments, and balms. It is commonly recognized that allantoin can hasten the healing process of wounds. 

 

The p-hydroxyphenylglycine segment in the glyoxylic acid market is expected to grow at the fastest CAGR over the forecast period. A major factor in the p-hydroxyphenylglycine segment's rapid growth is its growing use in pharmaceutical applications, particularly in the synthesis of antibiotics and other therapeutic compounds. The demand for high-purity intermediates like p-hydroxyphenylglycine is being driven by the world's growing need for sophisticated and efficient pharmaceutical products.  

 

Global Glyoxylic Acid Market, By Application:      

Where is glyoxylic acid commonly applied within the personal care industry? 

The personal care & cosmetics ingredients segment held the largest market share in the glyoxylic acid market. The segment with the highest revenue was personal care & cosmetics ingredients. Glyoxylic acid is an essential ingredient in hair straightening and smoothing products. The disulfide bonds in the hair are broken and reformed with its help, allowing the hair to straighten and reshape.  

 

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The pharmaceutical segment in the glyoxylic acid market is expected to grow at the fastest CAGR over the forecast period. The growing need for glyoxylic acid as a crucial precursor in the manufacture of active pharmaceutical ingredients (APIs), such as antibiotics and other medicinal chemicals, is the main factor propelling the expansion of the pharmaceutical industry.  

 

Regional Segment Analysis of the Global Glyoxylic Acid Market

• North America (U.S., Canada, Mexico) 
• Europe (Germany, France, U.K., Italy, Spain, Rest of Europe)
• Asia-Pacific (China, Japan, India, Rest of APAC)
• South America (Brazil and the Rest of South America) 
• The Middle East and Africa (UAE, South Africa, Rest of MEA)

 

North America Glyoxylic Acid Market Trends

Why is the demand for glyoxylic acid considered robust and mature in the North American market?

North America’s glyoxylic acid market is experiencing moderate growth, with demand centered in personal care and pharmaceutical sectors. The sophisticated pharmaceutical, personal care, specialty chemicals, and agrochemical sectors in the region are the main drivers of the robust, mature demand for glyoxylic acid in the North American market. Analysts estimate that in 2023, North America—which includes the United States and Canada accounted for around 25% of the world's use of glyoxylic acid.  The region's strong purchasing power, rising demand for clean-label and high-purity cosmetic and dermatological products, and established R&D and high-value chemical manufacturing infrastructure are important motivators.

 

Asia Pacific Glyoxylic Acid Market Trends

Where is the demand for glyoxylic acid rising most significantly within the Asia Pacific region?

The Asia Pacific Glyoxylic Acid Market is driven by rising demand in personal care, pharmaceuticals, and agrochemicals. Growing demand from a variety of end-use sectors, including agrochemicals, pharmaceuticals, and personal care, is propelling the Asia Pacific glyoxylic acid market's steady expansion. Glyoxylic acid, an important chemical intermediate, is widely used in the production of cosmetic ingredients, including allantoin and mandelic acid, as well as in the synthesis of pharmaceutical compounds and herbicides. One major driver of market expansion in the region is the growing personal care industry, especially in nations like China, India, and South Korea. Countries like China, India, and Japan are investing in advanced chemical manufacturing and expanding production capacity.

 

Japan Glyoxylic Acid Market Trends

What role does the aging population play in driving demand for glyoxylic acid in Japan?

Japan’s glyoxylic acid market is shaped by high-quality standards and innovation in pharmaceutical and cosmetic applications. The country emphasizes sustainable chemical practices and precision manufacturing. Demand is steady, supported by aging population needs and premium product preferences. The Japanese market for Glyoxylic acid is characterised by modest but steady demand, underpinned by application niches in personal-care, pharmaceutical intermediates, agrochemical synthesis and flavour/aroma compound.

 

China Glyoxylic Acid Market Trends

What factors are contributing to the steady expansion of the glyoxylic acid market in China?

China dominates the global glyoxylic acid market due to its large-scale production facilities and strong domestic demand. The market for glyoxylic acid in China is expanding steadily due to rising demand from a variety of end-use sectors, including agrochemicals, cosmetics, and pharmaceuticals. Glyoxylic acid is an essential step in the production of several substances, such as herbicides, vanillin, and allantoin. Domestic production capacities have been strengthened by rapid industrialization and improvements in chemical manufacturing technology.    

 

U.S Glyoxylic Acid Market Trends

What market growth is projected for the U.S. glyoxylic acid sector by 2035?

The U.S. glyoxylic acid market is expanding due to rising demand in cosmetics, aromas, and pharmaceutical formulations. Investments in sustainable production and R&D are driving innovation. The market is projected to grow significantly by 2035, supported by consumer trends and advanced chemical technologies. The main factor driving demand is its use as an intermediate chemical in high-value products including agrochemicals, medicines, and personal care items, especially in the synthesis of derivatives like allantoin and vanillin. 

 

Canada Glyoxylic Acid Market Trends  

Which sectors primarily support demand for glyoxylic acid in Canada?

Canada’s glyoxylic acid market is growing steadily, supported by demand in personal care and agrochemical sectors. The use of glyoxylic acid in specialized chemicals, personal care products, and medicines has a significant impact on the market's steady and moderate expansion in Canada. Although Canada's market share of glyoxylic acid in North America is expected to be around 23% in 2025, its emphasis on high-purity, low-volume consumption helps it to maintain a strategic position.  

 

Competitive Analysis:     

The report offers the appropriate analysis of the key organizations/companies involved within the global glyoxylic acid market, along with a comparative evaluation primarily based on their Type of offerings, business overviews, geographic presence, enterprise strategies, segment market share, and SWOT analysis. The report also provides an elaborate analysis focusing on the current news and developments of the companies, which includes Type development, innovations, joint ventures, partnerships, mergers & acquisitions, strategic alliances, and others. This allows for the evaluation of the overall competition within the market.  

 

Worldwide Top Key Players in The Glyoxylic Acid Market Include

• Hubei Shunhui Bio-Technology
• Stanchem Inc.
• Haihang Industry Co. Ltd.
• Akema Fine Chemicals
• Hubei Hongyuan Pharmaceutical Technology
• Merck KGaA
• WeylChem International GmbH
• Alfa Aesar
• Shandong Xinhua Pharmaceutical
• Zhonglan Industry Co. Ltd.
• Arochem Industries
• Tokyo Chemical Industry Co. Ltd.
• Others

 

Key Target Audience

• Market Players
• Investors
• End-users
• Government Authorities 
• Consulting And Research Firm
• Venture capitalists
• Value-Added Resellers (VARs)

 

Recent Development

• In August 2023, Guolin New Materials has launched its premium glyoxylic acid company to serve the European market. This expansion will enable the organization to reach more clients in the region and significantly increase its geographical footprint across Europe.

 

• In August 2023: Chemours sells its glycolic acid business to PureTech Scientific, LLC, backed by Iron Path Capital, for USD 137 million.

 

Market Segment    

This study forecasts revenue at the global, regional, and country levels from 2020 to 2035. Spherical Insights has segmented the glyoxylic acid market based on the following segments:

 

Global Glyoxylic Acid Market, By Derivatives  

• Allantoin
• Vanillin
• P-Hydroxyphenylglycine
• DL-P-Hydroxyphenyl Hydantoin
• 2-Hydroxyl-Phosphine Acetic Acid
• Others

 

Global Glyoxylic Acid Market, By Application

• Personal Care & Cosmetics Ingredients
• Pharmaceutical
• Aromas
• Agrochemicals
• Others

 

Global Glyoxylic Acid Market, By Regional Analysis

• North America
  • US
  • Canada
  • Mexico
• Europe
  • Germany
  • UK
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Rest of Asia Pacific
• South America
  • Brazil
  • Argentina
  • Rest of South America
• Middle East & Africa
  • UAE
  • Saudi Arabia
  • Qatar
  • South Africa
  • Rest of the Middle East & Africa