Global ACL Graft Market Size, Share, and COVID-19 Impact Analysis, By Graft Type (Autograft, Allograft, Xenograft, and Synthetic Grafts), By Injury Type (Sports Injuries and Non-Sports Injuries), By Age Group (19 Years & Below and Above 19 Years), and By Region (North America, Europe, Asia-Pacific, Latin America, Middle East, and Africa), Analysis and Forecast 2025 - 2035

Global ACL Graft Market Insights Forecasts to 2035

• The Global ACL Graft Market Size Was Estimated at USD 0.11 Billion in 2024
• The Market Size is Expected to Grow at a CAGR of around 6.94% from 2025 to 2035
• The Worldwide ACL Graft Market Size is Expected to Reach USD 0.23 Billion by 2035
• Asia Pacific is Expected to Grow the fastest during the forecast period.

The Global ACL Graft Market Size Was Worth around USD 0.11 Billion in 2024 and is predicted to Grow to around USD 0.23 Billion by 2035 with a compound annual growth rate (CAGR) of 6.94% from 2025 to 2035. The growing prevalence of orthopedic complications due to sports injuries and orthopedic diseases is driving the worldwide market demand for ACL graft.

Market Overview

The ACL Graft Market Size is the industry encompassing the surgical reconstruction of a torn anterior cruciate ligament (ACL) in the knee. In anterior cruciate ligament reconstruction (ACL reconstruction), a surgical tissue graft is replaced with the anterior cruciate ligament, located in the knee, to restore its function after an injury. Autografts, allografts, bridge-enhanced ACL repair, and synthetic tissue for ACL reconstruction are some of the graft options for ACL reconstruction. Emergence of minimally invasive surgical techniques, in the arthroscopic surgery, for improving recovery times and outcomes over traditional open surgery, has several benefits, including smaller incisions, reduced tissue damage, faster recovery times, and improved precision. There is an increasing need for improved graft material, like biologically enhanced or synthetic options, for minimizing complications and enhancing recovery. Adoption of biologic grafts, especially autografts, with an increasing emphasis on using biologically compatible material for promoting faster recovery and improving the success rate of ACL reconstruction surgeries. Adoption of healthcare infrastructure, advanced technologies, and enhanced surgical capabilities is providing growth opportunities in the ACL graft market.

Report Coverage

This research report categorizes the ACL graft market based on various segments and regions, forecasts revenue growth, and analyzes trends in each submarket. The report analyses the key growth drivers, opportunities, and challenges influencing the ACL graft market. Recent market developments and competitive strategies such as expansion, type launch, development, partnership, merger, and acquisition have been included to draw the competitive landscape in the market. The report strategically identifies and profiles the key market players and analyses their core competencies in each sub-segment of the ACL graft market.

Driving Factors

An increasing demand for orthopaedic surgery due to sports injuries, along with an increasing advancement in the graft for ACL reconstruction, is contributing to driving the market for ACL graft. It was estimated that approximately 3,00,000 ACL reconstructions are performed each year in the US. The availability of various ACL grafts, with an increasing number of ACL reconstruction surgeries, is responsible for market growth. Emergence of minimally invasive arthroscopic ACL reconstruction in knee surgery, with its numerous benefits, is driving the ACL graft market growth.

Restraining Factors

Risks associated with ACL graft surgery include infection, graft failure, persistent pain, and knee stiffness, limiting its adoption, which is hampering the market. Further, the increased cost of ACL reconstruction surgery, especially in emerging economies, is responsible for restricting the ACL graft market.

Market Segmentation

The ACL graft market share is classified into graft type, injury type, and age group.

• The autograft segment dominated the ACL graft market in 2024 and is projected to grow at a substantial CAGR during the forecast period.

Based on the graft type, the ACL graft market is divided into autograft, allograft, xenograft, and synthetic grafts. Among these, the autograft segment dominated the ACL graft market in 2024 and is projected to grow at a substantial CAGR during the forecast period. Autografts are preferred and cost-effective. Hamstring tendons and bone-patellar tendon-bone (BPTB) are the two most commonly used autografts in ACL reconstruction.

• The sports injuries segment accounted for the largest market share in 2024 and is anticipated to grow at the fastest CAGR during the forecast period.

Based on the injury type, the ACL graft market is divided into sports injuries and non-sports injuries. Among these, the sports injuries segment accounted for the largest market share in 2024 and is anticipated to grow at the fastest CAGR during the forecast period. ACL reconstruction aids in restoring knee stability and function, allowing athletes to regain strength and mobility in the affected joint; otherwise, there is an increased risk of further knee damage. The rising emphasis on sports injury prevention programs is contributing to the market growth.

• The above 19 years segment accounted for the largest market share in 2024 and is anticipated to grow at the fastest CAGR during the forecast period.

Based on the age group, the ACL graft market is divided into 19 years & below and above 19 years. Among these, the above 19 years segment accounted for the largest market share in 2024 and is anticipated to grow at the fastest CAGR during the forecast period. An increasing participation of older adults in sports and athletic activities and other physical activities makes them more prone to ACL injuries, anticipated to drive the market demand.

Regional Segment Analysis of the ACL Graft Market

• North America (U.S., Canada, Mexico) 
• Europe (Germany, France, U.K., Italy, Spain, Rest of Europe)
• Asia-Pacific (China, Japan, India, Rest of APAC)
• South America (Brazil and the Rest of South America) 
• The Middle East and Africa (UAE, South Africa, Rest of MEA)

North America is anticipated to hold the largest share of the ACL graft market over the predicted timeframe.

North America is anticipated to hold the largest share of the ACL graft market over the predicted timeframe. An increase in sports-related injuries, along with an increasing awareness about advanced surgical techniques, is driving the regional market for ACL graft. In addition, the increase in soft tissue repair procedures and the upsurging number of anterior cruciate ligament injuries are promoting the market growth.

Asia Pacific is expected to grow at a rapid CAGR in the ACL graft market during the forecast period. The growing prevalence of sports injuries and road accidents, and age-related orthopaedic complications, is driving the need for ACL reconstruction surgeries, which results in propelling the market demand. Further, the substantial infrastructure in healthcare infrastructure, especially in India, Indonesia, and Vietnam, for increased access to modern therapies, is contributing to driving market growth.

Competitive Analysis:

The report offers the appropriate analysis of the key organizations/companies involved within the ACL graft market, along with a comparative evaluation primarily based on their type of offering, business overviews, geographic presence, enterprise strategies, segment market share, and SWOT analysis. The report also provides an elaborative analysis focusing on the current news and developments of the companies, which includes type development, innovations, joint ventures, partnerships, mergers & acquisitions, strategic alliances, and others. This allows for the evaluation of the overall competition within the market.

List of Key Companies

• Arthrex Inc.
• Smith plus Nephew
• RTI Surgical
• AlloSource
• LifeNet Health
• Bone Bank Allografts
• MTF Biologics
• Zimmer Biomet
• Medtronic
• Johnson & Johnson Services Inc.
• JRF Ortho
• Others

Key Target Audience

• Market Players
• Investors
• End-users
• Government Authorities 
• Consulting And Research Firm
• Venture capitalists
• Value-Added Resellers (VARs) 

Recent Development

• In September 2023, Sakra World Hospital introduced a synthetic tissue graft for the anterior cruciate ligament (ACL) during knee replacement surgery, marking the launch of the Artificial Ligament.

• In July 2022, AlloSource, one of the largest allograft providers in the U.S., which creates innovative cellular and tissue allografts to help surgeons heal their patients, announced the addition of a quadricep tendon to its AlloConnex line of tendons, ligaments, and fascia.

Market Segment

This study forecasts revenue at global, regional, and country levels from 2020 to 2035. Spherical Insights has segmented the ACL graft market based on the below-mentioned segments: 

Global ACL Graft Market, By Graft Type

• Autograft
• Allograft
• Xenograft
• Synthetic Grafts

Global ACL Graft Market, By Injury Type

• Sports Injuries
• Non-Sports Injuries

Global ACL Graft Market, By Age Group

• 19 Years & Below
• Above 19 Years

Global ACL Graft Market, By Regional Analysis

• North America
  • US
  • Canada
  • Mexico
• Europe
  • Germany
  • UK
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Rest of Asia Pacific
• South America
  • Brazil
  • Argentina
  • Rest of South America
• Middle East & Africa
  • UAE
  • Saudi Arabia
  • Qatar
  • South Africa
  • Rest of the Middle East & Africa