Table of Contents
Historical Data, Premium Insights, Market Dynamic, Analysis and Projection, By Product, Analysis and Projection, By Application, Analysis and Projection, By End-Use, Analysis and Projection, By Regional Analysis, Competitive Landscape, Company Profiles, Market Revenue, Sale & Price Analysis
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According to a research report published by Spherical Insights & Consulting, The Global Targeted Protein Degradation Market Size Expected to Grow from USD 520.4 Million in 2023 to USD 3420.4 Million by 2033, at a CAGR of 20.72% during the forecast period 2023-2033.
Browse 210 market data Tables and 45 Figures spread through 190 Pages and in-depth TOC on the Global Targeted Protein Degradation Market Size, Share, and COVID-19 Impact Analysis, By Type (PROTAC, Molecular Glues), By Application (Drug Discovery, Therapy Development), and By Region (North America, Europe, Asia Pacific, Latin America, Middle East, and Africa), Analysis and Forecast 2023 – 2033
The targeted protein degradation (TPD) market is the industry dedicated to the development and commercialization of therapeutics, technologies, and research tools that selectively degrade disease-causing proteins. In contrast to conventional inhibitors, TPD-based medicines, including PROTACs (Proteolysis-Targeting Chimeras) and molecular glues, leverage the body's degradation machinery to target and remove specific proteins responsible for cancer, neurodegenerative diseases, and autoimmune diseases. Moreover, the targeted protein degradation (TPD) market is driven by progress in PROTACs, molecular glues, and artificial intelligence-based drug discovery. Growing incidence of cancer, neurodegenerative, and autoimmune diseases drives demand for targeted treatments. Rising investments in biotech R&D, pharma company collaborations, and advances in proteomics and structural biology further boost market growth, improving precision medicine development. However, low research expenses, cumbersome drug development protocols, and regulatory issues hinder market growth. Inadequate knowledge of protein interactions, possible off-target effects, and scalability problems further inhibit the general adoption of targeted protein degradation therapy.
The PROTAC segment accounted for the largest share of the global targeted protein degradation market in 2023 and is anticipated to grow at a significant CAGR during the forecast period.
On the basis of type, the global targeted protein degradation market is divided into PROTAC and molecular glues. Among these, the PROTAC segment accounted for the largest share of the global Targeted Protein Degradation market in 2023 and is anticipated to grow at a significant CAGR during the forecast period. This is because of their advanced development phase, expanding clinical pipeline, and robust pharmaceutical investments. PROTACs provide high specificity, improved drug efficacy, and the potential to target previously "undruggable" proteins, and thus are the leading segment in targeted protein degradation therapies.
The drug discovery segment accounted for a substantial share of the global targeted protein degradation market in 2023 and is anticipated to grow at a rapid pace during the projected period.
On the basis of the application, the global targeted protein degradation market is divided into drug discovery and therapy development. Among these, the drug discovery segment accounted for a substantial share of the global targeted protein degradation market in 2023 and is anticipated to grow at a rapid pace during the projected period. This is due to surging biotech and pharma investment in developing new PROTACs and molecular glues. Rising demand for cutting-edge therapeutics, development of AI-enabled screening, proteomics, and structural biology, and increased research collaboration further propel drug discovery leadership of this market.
North America is projected to hold the largest share of the global targeted protein degradation market over the projected period.
North America is projected to hold the largest share of the global targeted protein degradation market over the projected period. This is driven by strong biopharmaceutical R&D, advanced drug discovery infrastructure, and significant investments in PROTACs and molecular glues. The U.S. leads in clinical trials, backed by major biotech firms, academic collaborations, and government funding, accelerating the adoption of targeted protein degradation therapies for various diseases.
Europe is expected to grow at the fastest CAGR of the global targeted protein degradation market during the projected period. This is driven by rising biotech investments, the high presence of the pharmaceutical industry, and drug discovery government support. Germany, the U.K., and Switzerland are leading research on PROTACs and molecular glues. Increased collaboration between pharma companies and academic institutions further fuel market growth in the region.
Company Profiling
Major vendors in the global targeted protein degradation market are Thermo Fisher Scientific, Inc., Merck KGaA, Bayer AG, Promega Corporation, Bio-Techne, MedChemExpress, BPS Bioscience, Inc., LifeSensors Inc., BroadPharm, BOC Sciences, a nd Others.
Key Target Audience
Recent Development
Market Segment
This study forecasts revenue at global, regional, and country levels from 2023 to 2033. Spherical Insights has segmented the global targeted protein degradation market based on the below-mentioned segments:
Global Targeted Protein Degradation Market, By Type
Global Targeted Protein Degradation Market, By Application
Global Targeted Protein Degradation Market, By Regional
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