Global Bone Grafts And Substitutes Market Size To Exceed USD 6.85 Billion By 2033: Market Study Report

RELEASE DATE: May 2025 Author: Spherical Insights
The Global Bone Grafts And Substitutes Market Size is Expected to Grow from USD 3.56 Billion in 2023 to USD 6.85 Billion by 2033, at a CAGR of 6.76% during the forecast period 2023-2033

Table of Contents

Historical Data, Premium Insights, Market Dynamic, Analysis and Projection, By Product, Analysis and Projection, By Application, Analysis and Projection, By End-Use, Analysis and Projection, By Regional Analysis, Competitive Landscape, Company Profiles, Market Revenue, Sale & Price Analysis


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Global Bone Grafts And Substitutes Market Size To Exceed USD 6.85 Billion By 2033

 

According to a research report published by Spherical Insights & Consulting, The Global Bone Grafts And Substitutes Market Size is Expected to Grow from USD 3.56 Billion in 2023 to USD 6.85 Billion by 2033, at a CAGR of 6.76% during the forecast period 2023-2033.  

Browse 210 market data Tables and 45 Figures spread through 190 Pages and in-depth TOC on the

Global Bone Grafts And Substitutes Market Size, Share, and COVID-19 Impact Analysis, By Material Type (Allograft and Synthetic), By Application (Craniomaxillofacial, Dental, Foot & Ankle, Joint Reconstruction, Long Bone, and Spinal Fusion), and By Region (North America, Europe, Asia-Pacific, Latin America, Middle East, and Africa), Analysis and Forecast 2023 – 2033

The global bone grafts and substitutes market refers to the industry providing medical supplies for bone regeneration, replacement, or repair in cases of fractures, bone defects, or orthopedic procedures. For operations like spinal fusion, dental implants, and trauma surgeries, bone transplants and substitutes are crucial. Natural bone grafts (autografts and allografts) and synthetic substitutes such as ceramic-, polymer-, and composite-based grafts are both available in this market. The key primary factors for the growth of the bone grafts and substitutes market include the aging of the population, the rise in bone-related diseases, the development of regenerative medicine, and the need for less invasive procedures. Additionally, strict rules and regulations related to health care, the existence of major players in the biotechnology and healthcare sectors, and technical developments each affect the market. However, many patients cannot afford the high cost of treatments and materials, specifically recent synthetic and bioengineered which shrinks the market growth.

The allograft segment accounted for the largest revenue share in 2023 and is projected to grow at a significant CAGR during the forecast period.

On the basis of material type, the global bone grafts and substitutes market is divided into allograft and synthetic. Among these, the allograft segment accounted for the largest revenue share in 2023 and is projected to grow at a significant CAGR during the forecast period. The segment growth can be attributed because of its shown effectiveness, it has a sizable market, provides greater structural support, promotes bone healing, eliminates the need for additional surgery, and speeds up recovery.

The spinal fusion segment accounted for the highest revenue share in 2023 and is anticipated to grow at a substantial CAGR during the forecast period.

On the basis of application, the global bone grafts and substitutes market is divided into craniomaxillofacial, dental, foot & ankle, joint reconstruction, long bone, and spinal fusion. Among these, the spinal fusion segment accounted for the highest revenue share in 2023 and is anticipated to grow at a substantial CAGR during the forecast period. The segment growth is driven by the growing incidence of orthopedic conditions, particularly in the elderly, and the extensive use of bone grafts for spinal stability and restoration.

North America is anticipated to hold the largest share of the global bone grafts and substitutes market over the predicted timeframe.

North America is anticipated to hold the largest share of the global bone grafts and substitutes market over the predicted timeframe.  Among the primary trends promoting the demand for bone grafts and substitutes in North America are the growing elderly population, the rise in sports injuries, and the rise in deadly accidents.  Additionally, the region's adoption of these goods is being fueled by several orthopedic doctors who perform bone graft surgeries, beneficial reimbursement policies, and a well-established healthcare US healthcare market dominates the North America market.

Asia Pacific is expected to grow at the fastest CAGR in the global bone grafts and substitutes market during the forecast period. The regional growth can be attributed to the requirement for bone grafts and substitutes is being encouraged by the region's sizable patient base with orthopedic diseases.  The market is expanding due to the rising frequency of orthopedic ailments brought on by the growing aging population, especially in nations like China. The APAC market is anticipated to be driven by a larger patient pool, as well as increased expenditures generated by market players to increase their footprint in the region.

Major vendors in the global bone grafts and substitutes market are NuVasive, Inc., Smith + Nephew, Medtronic, Orthofix Medical, Inc., OST Laboratories, Zimmer Biomet, Geistlich Pharma AG, Stryker, Biobank, AlloSource, DePuy Synthes (Johnson & Johnson), Baxter, and Others.

Key Target Audience

  • Market Players
  • Investors
  • End-users
  • Government Authorities 
  • Consulting and Research Firm
  • Venture capitalists
  • Value-Added Resellers (VARs)

        

Recent Development

  • In October 2023, Orthofix Medical Inc. announced the 510k approval and full commercial launch of OsteoCoveTM, an innovative bioactive synthetic graft. OsteoCove, which comes in putty and strip form, offers exceptional bone-forming qualities for various orthopedic and spine procedures.

 

 

Market Segment

 

This study forecasts revenue at global, regional, and country levels from 2023 to 2033. Spherical Insights has segmented the global bone grafts and substitutes market based on the below-mentioned segments: 

 

Global Bone Grafts And Substitutes Market, By Material Type

  • Allograft
  • Synthetic

 

Global Bone Grafts And Substitutes Market, By

  • Craniomaxillofacial
  • Dental
  • Foot & Ankle
  • Joint Reconstruction
  • Long Bone
  • Spinal Fusion

 

Global Bone Grafts And Substitutes Market, Regional

 

  • North America
    • US
    • Canada
    • Mexico

 

  • Europe
    • Germany
    • Uk
    • France
    • Italy
    • Spain
    • Russia
    • Rest of Europe

 

  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Australia
    • Rest of Asia Pacific

 

  • South America
    • Brazil
    • Argentina
    • Rest of South America

 

  • Middle East & Africa
    • UAE
    • Saudi Arabia
    • Qatar
    • South Africa
    • Rest of the Middle East & Africa

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