United States Trypsin Market Size, Share, and COVID-19 Impact Analysis, By Source (Bovine, Porcine, and Others), By Application (Biotechnology & Pharmaceutical Industry, Food Industry, Cosmetics and Personal Care, Waste Treatment, and Others), and United States Trypsin Market Insights, Industry Trend, Forecasts to 2035

United States Trypsin Market Insights Forecasts to 2035

• The US Trypsin Market Size Was Estimated at USD 31.8 Million in 2024
• The Market Size is Expected to Grow at a CAGR of around 4.75% from 2025 to 2035
• The US Trypsin Market Size is Expected to Reach USD 53.0 Million by 2035

According to a Research Report Published by Spherical Insights & Consulting, The United States Trypsin Market Size is anticipated to Reach USD 53.0 Million by 2035, Growing at a CAGR of 4.75% from 2025 to 2035. The expansion of the United States Trypsin market is propelled by increasing demand for medicinal applications and protein digestion, as well as advancements in enzyme technology.

Market Overview

Trypsin is an important digestive enzyme that aids in breaking down proteins into smaller peptides and amino acids necessary for the repair of tissues, synthesis of hormones, muscle building, and other variety of other body functions. Trypsin is a core digestive enzyme used the digest proteins, and it is expected to see extensive market growth since the use of trypsin across many varied ways has significantly increased, such as in detergents, food science research, medicines, and leather-bating. New methods using trypsin and ongoing research are shaping the use of trypsin in creating or producing foods and medications. The exceptional ability of trypsin to hydrolyse proteins in the presence of water means that the enzyme is widely used in the research and development of pharmaceuticals, food, and the environment. Trypsin is also used as a raw material in internal medicine, in particular, clinical surgery and the treatment of endocrine disorders. To assist cut waste and boost productivity in the food, beverage, and pharmaceutical industries, the usage of enzyme catalysts has been expanded for commercial use. Furthermore, TRYPSIN VI, regarded as one of the best sources of trypsin, has been used in nutraceuticals, specifically as a digestive supplement for human and veterinary usage and as an anti-inflammatory. Further propelling market expansion is the increased focus on drug development and discovery. A prognostic marker for the treatment of colorectal cancer, tumor-associated trypsin inhibitor (TATI), is offered by Merck Millipore, a significant player in the US market, in several forms. When combined with trypsin, TATI can lessen tissue damage in some cancer types by blocking trypsin and other proteases, which enhances diagnostic outcomes. In the upcoming years, it is anticipated that these advancements in the industry will further raise demand.

Report Coverage

This research report categorizes the market for the United States trypsin market based on various segments and regions and forecasts revenue growth and analyses trends in each submarket. The report analyses the key growth drivers, opportunities, and challenges influencing the United States trypsin market. Recent market developments and competitive strategies such as expansion, product launch, development, partnership, merger, and acquisition have been included to draw the competitive landscape in the market. The report strategically identifies and profiles the key market players and analyses their core competencies in each sub-segment of the United States trypsin market.

Driving Factors

The growth of the United States trypsin market is boosted by the rising need for trypsin in cell culture research and biopharmaceutical R&D. Trypsin is essential for drug discovery and regenerative medicine since it is used in tissue culture cell separation, peptide mapping, and protein digestion. The need for trypsin has been significantly increased by the growth in the production of monoclonal antibodies (mAb) and developments in recombinant protein therapy. The industry is also being driven by Merck and Thermo Fisher Scientific, which have expanded their enzyme product lines to satisfy growing demands in proteomics and cell culture.

Restraining Factors

The United States trypsin market faces obstacles like strict regulatory requirements and the standardisation of quality issues. Trypsin must adhere to stringent purity and safety standards established by regulatory agencies, including the FDA, EMA, and EFSA, because it is a commonly used enzyme in food processing, biopharmaceuticals, and cosmetics. Batch homogeneity may be impacted by inconsistent source-derived trypsin (bovine or porcine), drawing regulatory notice and delaying approval.

Market Segmentation

The United States trypsin market share is classified into source and application.

• The bovine segment held the largest market share in 2024 and is expected to grow at a remarkable CAGR during the forecast period.

The United States trypsin market is segmented by source into bovine, porcine, and others. Among these, the bovine segment held the largest market share in 2024 and is expected to grow at a remarkable CAGR during the forecast period. The segment is driven by its unique cleavage activity for extensive application in a variety of disciplines. In comparison to other proteases, it is not just widely accessible but also reasonably priced. Prominent businesses like Thermo Fisher Scientific and Merck Millipore also provide cell culture-compatible bovine trypsin solutions that enable a variety of applications. Further propelling market expansion is anticipated to be the expanding use of research and development in the pharmaceutical and academic sectors.

• The biotechnology & pharmaceutical industry segment held the highest revenue share in 2024 and is expected to grow at a significant CAGR during the forecast period.

Based on the application, the United States trypsin market is segmented into biotechnology & pharmaceutical industry, food industry, cosmetics and personal care, waste treatment, and others. Among these, the biotechnology & pharmaceutical industry segment held the highest revenue share in 2024 and is expected to grow at a significant CAGR during the forecast period. The segmental growth is propelled by high-throughput screening techniques, and trypsin is frequently employed to investigate protein interactions with possible drug candidates. This helps to understand the structure-function correlations in target proteins, which aids in the creation of new treatments. One of the most inventive sectors is the pharmaceutical industry, where businesses are investing in the creation of premium natural proteins and enzymes.

Competitive Analysis:

The report offers the appropriate analysis of the key organizations/companies involved within the United States trypsin market, along with a comparative evaluation primarily based on their product offering, business overviews, geographic presence, enterprise strategies, segment market share, and SWOT analysis. The report also provides an elaborate analysis focusing on the current news and developments of the companies, which includes product development, innovations, joint ventures, partnerships, mergers & acquisitions, strategic alliances, and others. This allows for the evaluation of the overall competition within the market.

List of Key Companies

• Promega
• Agilent Technologies Inc
• Thermo Fisher Scientific Inc
• Merck Millipore
• Bio Rad Laboratories 
• Geno Technology 
• Worthington Biochemical Corporation
• Corning 
• GE Healthcare
• Others

Key Target Audience

• Market Players
• Investors
• End-users
• Government Authorities 
• Consulting and Research Firm
• Venture capitalists
• Value-Added Resellers (VARs)

Market Segment

This study forecasts revenue at the United States, regional, and country levels from 2020 to 2035. Spherical Insights has segmented the United States trypsin market based on the following segments:

United States Trypsin Market, By Source

• Bovine, Porcine
• Others

United States Trypsin Market, By Application

• Biotechnology & Pharmaceutical Industry
• Food Industry
• Cosmetics and Personal Care
• Waste Treatment
• Others