North America Nucleic Acid Isolation and Purification Market Size, Share, and COVID-19 Impact Analysis, By Product (Kits & Reagents, Instruments), By Type (DNA Isolation & Purification, and RNA Isolation & Purification), By Application (Precision Medicine, Diagnostics, Drug Discovery & Development, Agriculture and Animal Research, and Other), By End-use (Academic Research Institutes, Pharmaceutical & Biotechnology Companies, Contract Research Organizations, Hospitals and Diagnostic Centers, and Other), and North America Nucleic Acid Isolation and Purification Market Insights, Industry Trend, Forecasts to 2035

North America Nucleic Acid Isolation and Purification Market Insights Forecasts to 2035

• The North America Nucleic Acid Isolation and Purification Market Size Was Estimated at USD 2.32 Billion in 2024
• The Market Size is Expected to Grow at a CAGR of around 9.80% from 2025 to 2035
• The North America Nucleic Acid Isolation and Purification Market Size is Expected to Reach USD 6.49 Billion by 2035

According to a Research Report Published By Spherical Insights & Consulting, The North America Nucleic Acid Isolation and Purification Market Size is Anticipated to Reach USD 6.49 Billion by 2035, Growing at a CAGR of 9.80% from 2025 to 2035. The North America Nucleic Acid Isolation and Purification market Size is fueled by the increased investments in personalized medicine, advances in genetic research, the growing demand for molecular diagnostics, and the growing use of vaccines and treatments based on nucleic acids. Further driving market growth is anticipated from the increase of pharmaceutical and biotechnology R&D activities, as well as the incorporation of automation into laboratory workflows.

Market Overview

The Nucleic Acid Isolation and Purification Market Size refers to the industry devoted to the creation, manufacturing, and marketing of goods, services, and technology for the extraction and purification of nucleic acids, such as DNA and RNA, from biological materials for use in forensic, medical, diagnostic, and research purposes.

The market for nucleic acid isolation and purification is expected to grow rapidly due to increased demand in the fields of genomics, diagnostics, and personalized medicine. Technological developments are improving accessibility and efficiency, especially in automation and point-of-care systems. The growing research infrastructure in emerging markets presents enormous promise.  Workflows are becoming more efficient with the integration of AI and cloud technology, and product innovation is being shaped by sustainability initiatives. The market is expected to be crucial to the future of precision healthcare and molecular biology as these trends come together.

Report Coverage

This research report categorizes the market for North America nucleic acid isolation and purification market based on various segments and regions and forecasts revenue growth and analyzes trends in each submarket. The report analyses the key growth drivers, opportunities, and challenges influencing the North America nucleic acid isolation and purification market. Recent market developments and competitive strategies such as expansion, product launch, development, partnership, merger, and acquisition have been included to draw the competitive landscape in the market. The report strategically identifies and profiles the key market players and analyses their core competencies in each sub-segment of the North America nucleic acid isolation and purification market.

Driving Factors

The increasing spending on molecular diagnostics, personalized medicine, and genomics.  Lab workflows are being revolutionized by automation, which improves sample purity, speed, and consistency.  Rapid advancements in precision healthcare and genetic research are supported by the growing need for dependable, high-throughput solutions. Innovation is still fueled by funding from the public and commercial sectors. All of these elements work together to position the market for long-term growth in both clinical and research contexts.

Restraining Factors

The efficiency and accuracy of nucleic acid separation techniques, their expensive cost, continues to be a major deterrent to adoption. These technologies are difficult for smaller institutions with tighter R&D funds to afford. In the upcoming years, this financial limitation can impede the expansion of the market overall.

Market Segmentation

The North America nucleic acid isolation and purification market share is classified into product, type, application, and end use.

• The kits and reagents segment dominated the market in 2024 and is projected to grow at a substantial CAGR during the forecast period.

The North America nucleic acid isolation and purification market is segmented by product into kits & reagents, instruments. Among these, the kits and reagents segment dominated the market in 2024 and is projected to grow at a substantial CAGR during the forecast period. The growth is driven by the growing need for affordable, dependable, and easy-to-use solutions in molecular research and diagnostics.  Because of its effectiveness in separating high-quality nucleic acids, the sector has broad adoption in academic institutions and clinical labs. Reliable and user-friendly reagents are becoming more and more necessary as point-of-care diagnostics, where quick nucleic acid extraction is essential, gain more attention. The segment is crucial to the advancement of genomic and personalized medicine applications, and its growth is further supported by ongoing innovation in reagent formulations and the growing preference for ready-to-use kits.

• The DNA isolation and purification segment held a significant share in 2024 and is expected to grow at a significant CAGR during the forecast period.

The North America nucleic acid isolation and purification market is segmented by type into DNA isolation & purification and RNA isolation & purification. Among these, the DNA isolation and purification segment held a significant share in 2024 and is expected to grow at a significant CAGR during the forecast period. The segmental growth is due to the extensive application in biopharmaceutical development, clinical diagnostics, forensics, and genetic research.  Improvements in extraction technologies and the growing need for high-quality DNA in PCR, gene therapy, and next-generation sequencing applications are driving segment expansion in both research and clinical contexts.

• The drug discovery and development segment held a significant share in 2024 and is expected to grow at a significant CAGR during the forecast period.

The North America nucleic acid isolation and purification market is segmented by application into precision medicine, diagnostics, drug discovery & development, agriculture and animal research, and other. Among these, the drug discovery and development segment held a significant share in 2024 and is expected to grow at a significant CAGR during the forecast period. The segmental growth is due to the growing use of nucleic acid-based methods for target identification, lead optimization, and biomarker discovery, as well as increased R&D expenditures in biopharmaceuticals. The use of nucleic acid separation solutions in this market is being accelerated by the need for high-quality DNA and RNA in preclinical and clinical processes, as well as developments in sequencing and molecular screening technologies.

• The hospital and diagnostics segment dominated the market in 2024 and is projected to grow at a substantial CAGR during the forecast period.

The North America nucleic acid isolation and purification market is segmented by end use into academic research institutes, pharmaceutical & biotechnology companies, contract research organizations, hospitals and diagnostic centers, and other. Among these, the hospital and diagnostic centers segment dominated the market in 2024 and is projected to grow at a substantial CAGR during the forecast period. The growth is driven by the growing use of assays based on nucleic acids for screening, monitoring, and disease diagnosis. The need for precise and quick molecular diagnostic solutions has increased due to the growing incidence of genetic abnormalities, cancer, and infectious diseases. The segment's impressive performance was further aided by the developing diagnostic infrastructure in North America and the increasing incorporation of automated nucleic acid extraction equipment in clinical workflows.

Competitive Analysis:

The report offers the appropriate analysis of the key organizations/companies involved within the North America nucleic acid isolation and purification market, along with a comparative evaluation primarily based on their product offering, business overviews, geographic presence, enterprise strategies, segment market share, and SWOT analysis. The report also provides an elaborative analysis focusing on the current news and developments of the companies, which includes product development, innovations, joint ventures, partnerships, mergers & acquisitions, strategic alliances, and others. This allows for the evaluation of the overall competition within the market.

List of Key Companies

• Thermo Fisher Scientific, Inc.
• Promega Corporation
• Merck KGaA
• Bio-Rad Laboratories, Inc.
• Takara Bio Inc.
• Illumina, Inc.
• Agilent Technologies
• F. Hoffmann-La Roche Ltd
• Others

Key Target Audience

• Market Players
• Investors
• End-users
• Government Authorities 
• Consulting and Research Firm
• Venture capitalists
• Value-Added Resellers (VARs)

Recent Development

• In October 2024, QIAGEN expanded its liquid biopsy portfolio with the improved EZ1&2 ccfDNA Kit. It enables entirely automated processing of higher sample quantities, which is beneficial for cancer research and biomarker development.

Market Segment

This study forecasts revenue at the North America, regional, and country levels from 2020 to 2035. Spherical Insights has segmented the North America nucleic acid isolation and purification market based on the below-mentioned segments:

North America Nucleic Acid Isolation and Purification Market, By Product

• Kits & Reagents
• Instruments

North America Nucleic Acid Isolation and Purification Market, By Type

• DNA Isolation & Purification
• RNA Isolation & Purification

North America Nucleic Acid Isolation and Purification Market, By Application

• Precision Medicine
• Diagnostics
• Drug Discovery & Development
• Agriculture and Animal Research
• Other

North America Nucleic Acid Isolation and Purification Market, By End-use

• Academic Research Institutes
• Pharmaceutical & Biotechnology Companies
• Contract Research Organizations
• Hospitals and Diagnostic Centers
• Other