Japan Hormone Replacement Therapy Market Size, Share, and COVID-19 Impact Analysis, By Product Type (Estrogen & Progesterone Replacement Therapy, HGH replacement therapy, Thyroid hormone replacement therapy, Testosterone Replacement Therapy, and Parathyroid Hormone Replacement),, By Route Of Administration (Oral, Parenteral, Transdermal, and Others), By Disease Type (Menopause, Hypothyroidism, Male Hypogonadism, Growth Hormone Deficiency And Hypoparathyroidism) and Japan Hormone Replacement Therapy Market Insights, Industry Trend, Forecasts to 2035

Japan Hormone Replacement Therapy Market Insights Forecasts to 2035

• The Japan Hormone Replacement Therapy Market Size Was Estimated at USD 1,342.6 Million in 2024
• The Market Size is Expected to Grow at a CAGR of Around 6.04% from 2025 to 2035
• The Japan Hormone Replacement Therapy Market Size is Expected to Reach USD 2,560.5 Million by 2035

According to a Research Report Published by Spherical Insights & Consulting, The Japan Hormone Replacement Therapy Market Size is anticipated to reach USD 2,560.5 Million by 2035, Growing at a CAGR of 6.04% from 2025 to 2035. The Japan, the hormone replacement therapy market is expanding rapidly due to various factors, including a rise in hormonal disorders like menopause and hypogonadism, a rising aging population, rising awareness of hormone replacement therapy benefits and technological advancements.

Market Overview

The Hormone Replacement Therapy is a medical treatment that replaces hormones in the body, like estrogen, progesterone and testosterone, to treat symptoms of hormonal imbalance.  This is a treatment in which hormones are administered from the outside to replace or supplement the natural hormones in the body. Treatment is carefully regulated so that hormone levels stay within the right range to facilitate overall good health and reduce the detrimental effects of hormonal imbalance. The key factor that drives the growth of the market is the rising hormone-related disorders owing to various factors like changing lifestyle, stress and natural processes of aging. In addition, continuous technological advancements in hormone delivery devices, e.g., transdermal patches and implantable systems, are further increasing HRT convenience and specificity in its delivery. This facilitates patient compliance and improves the results of treatment, and boosts market growth. The rising preference for personalized or bioidentical HRT presents an opportunity for growth.

Report Coverage

This research report categorizes the market for the Japan hormone replacement therapy market based on various segments and regions and forecasts revenue growth and analyzes trends in each submarket. The report analyses the key growth drivers, opportunities, and challenges influencing the Japan hormone replacement therapy market. Recent market developments and competitive strategies such as expansion, product launch, development, partnership, merger, and acquisition have been included to draw the competitive landscape in the market. The report strategically identifies and profiles the key market players and analyses their core competencies in each sub-segment of the Japan hormone replacement therapy market.

Driving Factors

A number of factors drive the hormone replacement therapy market in Japan. Japan is the fastest-growing population country, which leads to various health issues such as osteoporosis, cardiovascular diseases, and menopausal symptoms, which drives the growth of the market. The change in lifestyle leads the hormonal imbalance disorders that have produced a rising demand for treatments like hormone replacement therapy. People are becoming aware of the health benefits of HRT makes a positive impact on the market. Additionally, the advancement in technologies expands the market growth.

Restraining Factors

The Japan hormone replacement therapy market has some obstacles that limit the market growth. One of the notable obstacles is the health risk and side effects associated with the treatment, which limit the market growth. The hormone replacement therapy requires a high cost, which may not be affordable for all patients.

Market Segmentation

The Japan hormone replacement therapy Market share is classified into product, route of administration, and disease type.

• The estrogen & progesterone replacement therapy segment held the highest share of the market in 2024 and is expected to grow at a rapid CAGR during the forecast period.

The Japan hormone replacement therapy market is segmented by product into estrogen & progesterone replacement therapy, hGH replacement therapy, thyroid hormone replacement therapy, testosterone replacement therapy, and parathyroid hormone replacement. Among these, the estrogen & progesterone replacement therapy segment held the highest share in 2024 and is expected to grow at a rapid CAGR during the forecast period. This is due to the increased number of women suffering from menopause.

• The oral segment dominated the market in 2024 and is expected to grow at a significant CAGR during the forecast period.

The Japan hormone replacement therapy market is segmented by route of administration into oral, parenteral, transdermal, and others. Among these, the oral segment dominated the market in 2024 and is expected to grow at a significant CAGR during the forecast period. This segmental growth is attributed to its easy administration and high prescription rate. Moreover, most HRT products generally include pills & tablets.

• The menopause segment held the largest share in 2024 and is expected to grow at a significant CAGR during the forecast period.

The Japan hormone replacement therapy market is segmented by disease type into menopause, hypothyroidism, male hypogonadism, growth hormone deficiency and hypoparathyroidism. Among these, the menopause held the largest share in 2024 and is expected to grow at a significant CAGR during the forecast period. This is due to the rising number of women suffering from menopause. menopause age differs depending on several factors; natural factors like environment and heredity modify menopause age in a person to some degree.

Competitive Analysis:

The report offers the appropriate analysis of the key organizations or companies involved within the Japan hormone replacement therapy market, along with a comparative evaluation primarily based on their product offering, business overviews, geographic presence, enterprise strategies, segment market share, and SWOT analysis. The report also provides an elaborative analysis focusing on the current news and developments of the companies, which includes product development, innovations, joint ventures, partnerships, mergers & acquisitions, strategic alliances, and others. This allows for the evaluation of the overall competition within the market.

List of Key Companies

• Pfizer Japan Inc.
• MSD K.K.
• Bayer Yakuhin, Ltd.
• Novo Nordisk Pharma Ltd
• AbbVie GK
• Takeda Pharmaceutical Company Limited
• Aska Pharmaceutical Co., Ltd.
• Others

Recent Developments

• In January 2022, for paediatric hormone deficiency, Japans Ministry of Health and Welfare approved NGENLA (somatrogon), a once weekly long-acting growth hormone injection by Pfizer and OPKO Health

Key Target Audience

• Market Players
• Investors
• End-users
• Government Authorities 
• Consulting and Research Firm
• Venture capitalists
• Value-Added Resellers (VARs)

Market Segment

This study forecasts revenue at the Japan, regional, and country levels from 2020 to 2035. Spherical Insights has segmented the Japan hormone replacement therapy Market based on the below-mentioned segments:

Japan Hormone Replacement Therapy Market, By Product

• Estrogen & Progesterone Replacement Therapy
• HGH replacement therapy
• Thyroid hormone replacement therapy
• Testosterone Replacement Therapy
• Parathyroid Hormone Replacement

Japan Hormone Replacement Therapy Market, By Route of Administration

• Oral
• Parenteral
• Transdermal
• Others

Japan Hormone Replacement Therapy Market, By Disease Type

• Menopause
• Hypothyroidism
• Male Hypogonadism
• Growth Hormone Deficiency
• Hypoparathyroidism