World’s Top 50 Companies in Synthetic Biology Market 2025 Watch list: Statistical Report (2024–2035)

Description

According to a research report published by Spherical Insights & Consulting, The Global Synthetic Biology Market Size is projected to Grow from USD 18.0 Billion in 2024 to USD 221.9 Billion by 2035, at a CAGR of 25.65% during the forecast period 2025–2035. The market for synthetic biology is in greater demand, driven by the quick development of genetic engineering tools, particularly CRISPR, and the declining cost of DNA synthesis and sequencing, which improve efficiency and accessibility. Another important driver is the growing need for bio-based, sustainable products such as biofuels, bioplastics, and designed medicines.

 

Introduction

Synthetic biology is a multidisciplinary field that applies engineering concepts to biology to create, repurpose, or build biological systems and components such as gene circuits, DNA sequences, and entire organisms for specific, useful applications. In order to produce new systems with useful applications, synthetic biology blends science and engineering to construct and alter biological entities, including cells, enzymes, and genetic circuits.  Using standardized genetic components, scientists can quickly put together small bits to create complicated systems for applications such as creating enhanced biofuels, renewable chemicals, and other bio products that aren't present in nature. Support from the government and business community is strong, and the sector is driven by technological advancements in DNA synthesis and sequencing, as well as falling costs. Amyris GenScript, Novozymes, Ginkgo Bioworks, Agilent Technologies, Merck KGaA, and Thermo Fisher Scientific are important participants. Applications in cellular recording, diagnostics, and therapeutic genome editing are becoming more and more in demand. Ginkgo Bioworks and Sojitz signed a legally binding agreement to bring synthetic biology research and development to the Japanese industry.

 

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Synthetic Biology Market Size & Statistics

• The Market Size for Synthetic Biology Was Estimated to be worth USD 18.0 Billion in 2024.
• The Market Size is Going to Expand at a CAGR of 25.65% between 2025 and 2035.
• The Global Synthetic Biology Market Size is anticipated to reach USD 221.9 Billion by 2035.
• North America is expected to generate the highest demand during the forecast period in the Synthetic Biology Market
• Asia Pacific is expected to grow the fastest during the forecast period in the Synthetic Biology Market.

 

Regional growth and demand                                   

Asia Pacific is expected to grow the fastest during the forecast period in the synthetic biology market. The market for synthetic biology is now growing in the Asia Pacific due to the rapidly growing economies of China and India, which support the development of biotechnology. China's concerted efforts to establish itself as a regional leader in the sector are reflected in its strategic GIDL programs. Multinational biotech companies are establishing R&D and manufacturing hubs in the region due to the region's competitive production prices and highly qualified scientific personnel. In the meantime, growing consumer demand for healthcare products and biopharmaceuticals keeps driving market growth.

 

North America is expected to generate the highest demand during the forecast period in the synthetic biology market. The synthetic biology market with the quickest rate of growth throughout the study period is anticipated to be in North America, due to its strong R&D capabilities and significant financing from both public organisations (NIH, NSF, and DOE) and top biotech corporations in the US and Canada. North America is expected to dominate the synthetic biology market. With the help of top-notch universities, research facilities, and advantageous regulatory frameworks, the area is a leader in proteomics, drug discovery, genome structure prediction, and the development of innovative gene and cell therapies. These elements work together to guarantee North America's dominance in the field of synthetic biology, including robust innovation networks, institutional cooperation, and the need for innovative treatments.

 

Top 10 trends in the Synthetic Biology Market

• AI-Guided Design and Automation
• Automated Biofoundries & Cell-Free Systems
• Smart Biosensors & Synthetic Vaccines
• Predictive Strain Engineering & Microbial Consortia
• Modular, Scalable Biomanufacturing & Green Chemistry
• Expansion of Therapeutic and Industrial Applications
• Strategic Partnerships & Collaboration
• Cyberbiosecurity & Biosafety Controls
• Emerging Concepts Synthetic Organelles & Immunology
• Open Synthetic Biology & Bioconvergence

 

1. AI-Guided Design and Automation

In synthetic biology, the design build test learn cycle is being transformed by AI and machine learning. By identifying trends in sizable biological datasets and forecasting the best biomolecular structures for experimental testing, artificial intelligence techniques speed up the creation of hypotheses and genetic circuit designs. In order to significantly increase throughput and dependability, fully automated biofoundries robotics-driven labs integrate AI at every stage, coordinating DNA assembly, testing, and feedback-driven optimisation. Platforms that integrate cloud labs, self-driving experiments, and microfluidics allow for closed-loop DBTL procedures, which minimise human error and facilitate quick iterations.

 

2. Automated Biofoundries & Cell-Free Systems

Synthetic biology is changing as automated biofoundries and cell-free systems come together. Biofoundries quickly develop microorganisms for uses such as sustainable chemicals, diagnostics, and innovative biomaterials by using high-throughput robotic platforms to carry out design, build, test learn cycles with accuracy and scale. In the meantime, open, controlled, and quick prototyping and manufacturing of proteins, pathways, and biosensors are made possible by cell-free systems, which use transcription and translation machinery outside of living cells, eliminating the complexity of living things.

 

3. Smart Biosensors & Synthetic Vaccines

In synthetic biology, smart biosensors are developing into intelligent systems with integrated memory storage, computation, and self-calibration.This allows for point-of-care and portable diagnostics through standardised modular design and genetic circuit engineering. By improving specificity, sensitivity, and real-time connectivity, advanced CRISPR based biosensors and nanomaterial integration are speeding up and improving the accuracy of on-site disease diagnosis. Simultaneously, modular antigen scaffolds, DNA, RNA, and peptide constructs based synthetic vaccination platforms provide quick development, customisation, and adaptation to new pathogens, revolutionising vaccine design with accuracy and flexibility.

 

4. Predictive Strain Engineering & Microbial Consortia

Microbial engineering is changing as a result of new developments in synthetic biology that combine engineered microbial consortia with predictive strain design. These days, adaptive algorithms and computational models predict the best strain changes and metabolic interactions in multi-species communities, allowing for adjustable behaviours like enhanced resilience and cooperative task division. Synthetic consortia, or SynComs, are intentionally designed to improve function, modularity, and stability over monocultures.

 

5. Modular, Scalable Biomanufacturing & Green Chemistry

Standardised, plug-and-play genetic components and efficient biomanufacturing pipelines are transforming sustainable chemical production through modular, scalable biomanufacturing in synthetic biology. Enzymes, promoters, and whole metabolic pathways are examples of modular genetic components that enable the quick assembly and optimisation of microbial biorefineries to transform renewable feedstocks into biofuels, bioplastics, medicines, and specialty chemicals, lowering dependency on petrochemicals and minimising environmental impact.

 

Empower your strategic planning:

Stay informed with the latest industry insights and market trends to identify new opportunities and drive growth in the synthetic biology market. To explore more in-depth trends, insights, and forecasts, please refer to our detailed report.

 

Top 21 Companies Leading the Synthetic Biology Market

1. Merck KGaA
2. Agilent Technologies
3. NOVOZYMES
4. Ginkgo Bioworks
5. Genscript
6. Thermo Fisher Scientific Inc
7. Amyris Inc
8. INTEGRATED DNA TECHNOLOGIES INC.
9. Illumina, Inc.
10. Precigen, Inc.
11. Twist Bioscience
12. Synthetic Genomics
13. Codexis
14. Synthego
15. Twist Bioscience
16. LanzaTech
17. Ecovative Design
18. Joyn Bio
19. Conagen
20. Huue
21. QIAGEN

 

1. Merck KGaA

Headquarters: Hesse, Germany

Merck KGaA, Darmstadt, Germany, is a global science and technology company headquartered in Darmstadt, Hesse, Germany. It operates across three primary business sectors healthcare, life science, and electronics. The company develops and manufactures prescription drugs for various therapeutic areas, including oncology, neurology, immunology, fertility, and endocrinology. In the Life Science sector, Merck KGaA provides tools, chemicals, and equipment for academic labs, biotech and pharmaceutical manufacturers, and the industrial sector. The Electronics division supplies advanced materials for the semiconductor and display industries. Merck KGaA has a global presence, serving customers in Europe, North America, Latin America, the Middle East & Africa, and the Asia-Pacific regions.

 

2. Agilent Technologies

Headquarters: Santa Clara, California

Agilent Technologies Inc. is a world leader in consumables, software, services, and laboratory equipment. With operations in more than 110 countries and its headquarters located in Santa Clara, California, the corporation supports sectors like environmental testing, food safety, diagnostics, and pharmaceuticals. With the help of Agilent's product line, which includes mass spectrometers, chromatography systems, and diagnostic instruments, scientists can provide precise and trustworthy results. Through innovation and client engagement, the company is dedicated to improving quality of life by offering solutions that increase laboratory efficiency and productivity.

 

3. NOVOZYMES

Headquarters: Bagsvaerd, Denmark

Novozymes is a world leader in industrial biotechnology, with its headquarters located in Bagsvaerd, Denmark. Producing enzymes, microbes, and biopharmaceutical substances, the company serves the food and beverage, pharmaceutical, household care, bioenergy, and agricultural sectors. By lowering energy, water, and raw material waste, Novozymes' creative solutions improve industrial performance while advancing sustainability. Novozymes and Chr. Hansen combined in January 2024 to establish Novonesis, a new company dedicated to developing biosolutions for a healthier business and world.

 

4. Ginkgo Bioworks

Headquarters: Massachusetts, USA

A pioneer in synthetic biology, Ginkgo Bioworks is referred to as the organism company. Across a variety of industries, including food, pharmaceuticals, speciality chemicals, and agriculture, it provides end-to-end services like organism engineering, fermentation, enzyme discovery, and biosecurity through its advanced cell programming platform. Custom microorganisms and biomolecules may be quickly designed and optimised in their highly automated foundries to replace conventional chemical processes.

 

5. Genscript

Headquarters: Jiangsu, China

Global biotech pioneer GenScript Biotech Corporation provides all-inclusive solutions for life science applications and research. Gene editing including CRISPR tools, antibody development, cell line engineering, biologics CDMO services, industrial synthetic products, DNA, peptide, and protein synthesis, and integrated cell treatment are among its primary offerings. In more than 100 nations, GenScript facilitates medication discovery, immunotherapy, vaccine development, and research.

 

Are you ready to discover more about the synthetic biology market?

The report provides an in-depth analysis of the leading companies operating in the global synthetic biology market. It includes a comparative assessment based on their product portfolios, business overviews, geographical footprint, strategic initiatives, market segment share, and SWOT analysis. Each company is profiled using a standardized format that includes:

 

Company Profiles

1. Merck KGaA

• Business Overview
• Company Snapshot
• Products Overview
• Company Market Share Analysis
• Company Coverage Portfolio
• Financial Analysis
• Recent Developments
• Merger and Acquisitions
• SWOT Analysis

1. Agilent Technologies
2. NOVOZYMES
3. Ginkgo Bioworks
4. Genscript
5. Thermo Fisher Scientific Inc
6. Amyris Inc
7. IBM
8. INTEGRATED DNA TECHNOLOGIES INC.
9. Others.

 

Conclusion

The synthetic biology market size is accelerating due to the growing need for novel treatments and the depletion of antibiotic pipelines; the synthetic biomedicine industry is expanding. Chronic diseases like HIV and cancer are also on the rise. This rise is further fuelled by rising demand for vaccines, protein-based therapies, synthetic medicines, and personalised medicine. In order to foster entrepreneurs and convert synthetic biology research into societal and economic impact, SynbiCITE, which is housed at Imperial College's engineering biology centre, has received critical support and proof-of-concept funding in the UK. In the meantime, growing uses in therapeutic research and targeted treatment highlight the industry's promising future.

 

About the Spherical Insights & Consulting

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